Designed with your needs in mind
Elfabrio is an enzyme replacement therapy (ERT) that was designed using a process called PEGylation (peg-eh-lay-shun). This process extends the half-life* so Elfabrio can stay for a long time in your body.
The Elfabrio half-life was also shown to increase over time as the medication stays in your body.
| * | Clinical studies have not shown that a long half-life results in a medicine working better or more safely. Infusions are every 2 weeks. |
What is the half-life?
The half-life of a treatment is how long it takes for the amount of the medicine in your body to decrease by half.
Elfabrio
half-life reaches*
Day 1
~80
Hours
78.9 ± 10.3 hours
Month 6
~96
Hours
96.5 ± 31.4 hours
Month 12
~120
Hours
121 ± 22 hours
A long half-life lets your doctors know that the medication in your body is measurable from infusion to infusion. This may help to show that your Elfabrio treatment is still present from dose to dose.
Picture a treatment built to last
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Long half-life† |
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Stays in your body between doses† |
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Half-life continues to increase over time†‡ |
| † | Elfabrio has an initial half-life of 78.9 ± 10.3 hours. Clinical studies have not shown that a long half-life results in a medicine working better or more safely. Infusions are every 2 weeks. |
| ‡ | The average half-life of Elfabrio was measured for 1 year in clinical studies. |
Need help talking to your doctor about Elfabrio?
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People like you
There’s nothing like hearing from other people who have Fabry disease so you know you are not alone on this journey.
Below you can see examples of the type of people who may be considered for Elfabrio treatment. Sofia and Rob are not actual patients, but they are based on people from the Elfabrio studies.
As more people are treated with Elfabrio, their real stories will be shared so other people with Fabry can learn from their experiences.
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Meet Sofia§
Sofia is currently on treatment for her Fabry disease. Sofia's Fabry has affected her kidneys, so her doctor continues to monitor how her kidneys are working. Sofia's Fabry has been well controlled since she started treatment, but there are some factors that she wants to talk to her doctor about. Sofia's doctor suggested she make an appointment so they can discuss what to do next.
Does Sofia’s journey sound similar to yours?
Learn more about how switching to Elfabrio may help| § | Not an actual patient. Patient symptoms will vary. Your doctor will determine the best course of therapy. |
Meet Rob§
Rob was just diagnosed with Fabry disease after one of his family members was diagnosed and he was recommended for testing. A genetic counselor confirmed his diagnosis. He will be discussing treatment options with his doctor at his upcoming appointment.
Does Rob’s journey sound similar to yours?
Learn more about how starting on Elfabrio may help| § | Not an actual patient. Patient symptoms will vary. Your doctor will determine the best course of therapy. |
